About St. Mary
The Cathedral of St. Mary of the Annunciation anchors Catholic life in Cape Girardeau, Missouri, offering three Sunday Masses — including a 7 AM early option and a 10:30 AM family Mass — plus daily 6 AM and 8 AM liturgies every weekday and Saturday. The cathedral's Sunday 8:30 AM Mass is broadcast on local radio and live-streamed on Facebook, extending its reach across southeast Missouri. Ministries include a parish food pantry, the Parish School of Religion, and affiliated St. Mary Cathedral Grade School and Notre Dame High School.
St. Mary is a Roman Catholic parish in Cape Girardeau, Missouri, part of the Diocese of Springfield-Cape Girardeau. The parish offers Mass 20 times per week, including Sunday at 7 AM and 8:30 AM and 10:30 AM. Confession is available on Tuesday, Saturday. View the full schedule below.
Mass Schedule
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Mass and sacrament times can change for holy days, seasons, and special events. Please confirm directly with the parish before visiting.
Confession Schedule
Tuesday
Saturday
Programs & Ministries
RCIA / OCIA (Becoming Catholic)
RCIA / OCIA
Schedule: Monday, 9 AM
Faith Formation & Religious Education
Faith Formation
Other Ministries
Family Life Ministry
All agesSchedule: seasonal
This year, the project of Family Life Ministry of St Mary's is the 'Pause & Pray Project' to encourage patience while driving.
Annual project
St. Mary Grade School Alumni Association
AdultsSt. Mary Grade School Alumni Association is currently updating their files of Alumni. If you attended St. Mary Cathedral Grade School, we would like to have your contact information!
Frequently Asked Questions
What are the Mass times at St. Mary? ▼
St. Mary Mass times: Sunday at 7 AM, 8:30 AM, 10:30 AM. Weekday Mass is also celebrated on Monday, Tuesday, Wednesday, Thursday, Friday.
When is confession at St. Mary? ▼
St. Mary confession times: Tuesday 4:30 PM - 5 PM; Saturday 3 PM - 4 PM, 3:15 PM - 4:15 PM. Confession is also known as the Sacrament of Reconciliation.
Is there a Saturday Vigil Mass at St. Mary? ▼
Yes, St. Mary celebrates Saturday Vigil Mass at 4:30 PM, 5:15 PM. The Saturday Vigil Mass fulfills the Sunday Mass obligation for Catholics.
Does St. Mary have daily Mass? ▼
Yes, St. Mary offers daily Mass on Monday, Tuesday, Wednesday, Thursday, Friday. Common weekday Mass times: 6 AM, 8 AM, 5:15 PM.
Where is St. Mary located? ▼
St. Mary is located at 615 William Street, Cape Girardeau, MO 63703. Get directions using the "Directions" button on this page.
Nearby Catholic Churches
St. Vincents Church
Cape Girardeau, MO
0.4 miles away
St. Vincent de Paul
Cape Girardeau, MO
0.4 miles away
St. John Henry Newman Center
Cape Girardeau, MO
0.7 miles away
Catholic Campus Ministry
Cape Girardeau, MO
0.8 miles away
St. Francis Chapel, St. Francis Healthcare
Cape Girardeau, MO
2.5 miles away
St. Augustine
Kelso, MO
7.7 miles away